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Proper Use of This Medicine
The recommended starting dose of MERIDIA is 10-milligrams administered once daily with or without food. If there is inadequate weight loss, the dose may be titrated after 4 weeks to a total of 15-mill
igrams taken once daily. The 5-milligram dose should be reserved for those patients that do not tolerate the 10-milligram dose. Blood pressure and heart rate changes should betaken into consideration
when making decisions regarding dose titration. Take this medication as prescribed. Do not take it more often or longer than directed. Use in combination with other appetite suppressant medicine is ge
nerally not recommended.
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Side Effects of This Medicine
Use Meridia with caution if you have uncontrolled high blood pressure; it could make the problem worse. Avoid Meridia completely if you've had a stroke or suffer from heart disease, heart failure, or
irregular heartbeat. Also avoid it if you have severe kidney or liver problems; the drug has not been tested under these conditions. Seizures are a rare, but possible, side effect. If you've had seizu
res in the past, use Meridia with caution. If you have a seizure while taking the drug, stop using it and call your doctor immediately.
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Precautions Before Using This Medicine
Older adults¡XMany medicines have not been studied specifically in older people. Therefore, it may not be known whether they work exactly the same way they do in younger adults. Although there is no sp
ecific information comparing use of Meridia in the elderly with use in other age groups, this medicine is not expected to cause different side effects or problems in older people than it does in young
er adults.
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Cautions
Do not take Meridia while you are taking or within 2 weeks of taking medicines with monoamine oxidase (MAO) inhibitor activity , such as isocarboxazid (e.g., Marplan), phenelzine (e.g., Nardil), proca
rbazine (e.g., Matulane), selegiline (e.g., Eldepryl), or tranylcypromine (e.g., Parnate). Do not take an MAO inhibitor within 2 weeks of taking Meridia. To do so may cause severe seizures, extremely
high blood pressure, or a life-threatening adverse effect called the serotonin syndrome.
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MERIDIA is a short-term drug that helps you to start losing weight and then keep on going when you are ready to carry on, on your own. Your body starts to build up a resistance to the effects of MERIDIA after a few weeks of treatment, which
When you are taking Meridia, it is especially important that your health care professional know if you are taking any of the following:
- Tramadol (e.g., Ultram) or
- Trazodone (e.g., D
esyrel) or
- Tryptophan or
- Venlafaxine (e.g., Effexor)¡XUsing these medicines with Meridia may increase the chance of developing a rare, but very serious, unwanted effect known as the serot
onin syndrome. Symptoms of this syndrome include confusion, diarrhea, fever, poor coordination, restlessness, shivering, sweating, talking or acting with excitement you cannot control, trembling or sh
aking, or twitching. If you develop these symptoms, contact your doctor as soon as possible
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Why is this drug prescribed?
Meridia (si-BYOO-tra-meen) is used together with a reduced-calorie diet to help you lose weight and to help keep the lost weight from returning. Meridia is thought to work by increasing the activity o
f certain chemicals, called norepinephrine and serotonin, in the brain. This medicine is approved for use only in people who are very overweight.
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